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abbott i stat alinity point  (Abbott Laboratories)

 
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    Abbott Laboratories abbott i stat alinity point
    Abbott I Stat Alinity Point, supplied by Abbott Laboratories, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/abbott i stat alinity point/product/Abbott Laboratories
    Average 86 stars, based on 1 article reviews
    abbott i stat alinity point - by Bioz Stars, 2026-05
    86/100 stars

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    Possible biochemical mechanisms of false-positive interferences in troponin assays: 1—Heterophile antibodies may cause false-positive results by acting as a bridge between capture and detection antibodies in the absence of cTn. Macrocomplexes (macro-cTn) reduce the plasma clearance of cTn, causing an increase in the circulating concentrations of complexed molecules that are eventually measured with the immunoassay. 2—PEG treatment induces the precipitation of macrocomplexes, leaving the uncomplexed cTn molecules in the supernatant after centrifugation of the sample.

    Journal: Journal of Cardiovascular Development and Disease

    Article Title: “Troponinosis”, the Cardiologist’s Curse—When Clinic–Laboratory Interaction Unveils the Mystery: A Case Report

    doi: 10.3390/jcdd10090378

    Figure Lengend Snippet: Possible biochemical mechanisms of false-positive interferences in troponin assays: 1—Heterophile antibodies may cause false-positive results by acting as a bridge between capture and detection antibodies in the absence of cTn. Macrocomplexes (macro-cTn) reduce the plasma clearance of cTn, causing an increase in the circulating concentrations of complexed molecules that are eventually measured with the immunoassay. 2—PEG treatment induces the precipitation of macrocomplexes, leaving the uncomplexed cTn molecules in the supernatant after centrifugation of the sample.

    Article Snippet: A significant difference in cTnI concentrations measured with an alternative immunoassay confirmed the interference (187.5 ng/L, measured with Abbott Abbott Alinity i STAT high sensitive Troponin I; sex-related 99° percentile: 34.2 ng/L), even accounting for the expected bias between methods [ ].

    Techniques: Clinical Proteomics, Centrifugation